Chaste tree is often used in the treatment of PMS, hyperprolactinaemia, acne, erratic ovulation, conditions of relative oestrogen excess such as PCOS, postnatal depression, uterine fibroids, endometriosis, amenorrhea, menorrhagia, oligomenorrhea, metrorrhagia, sleep maintenance insomnia and DUB (dysfunctional uterine bleeding).